1. Bölüm

Jean Smart

Dr. Ann Possible (voice)

Nicole Sullivan

Shego (voice)

Mindy Cohn

Ms. Whisp (voice)

Rider Strong

Brick Flagg (voice)

Phil Morris

Lieutenant Franklin / Infinity Guy / Mathematician (voice)

John DiMaggio

Dr. Drakken / Dr. Zeruda (voice)

April Winchell

Tricia Lipowski / Bernice (voice)

Shaun Fleming

Tim Possible / Jim Possible (voice)

Gary Cole

Dr. James Possible (voice)